Journal study finds TriCalm 'most effective OTC itch relief treatment'

SAN DIEGO - The journal Clinical, Cosmetic and Investigational Dermatology earlier this week published a study finding that Cosmederm Bioscience's TriCalm OTC itch relief solution was superior to diphenhydramine 2% and hydrocortisone 1%.

 

"The results of this study are a testament to TriCalm's value as the most effective over-the-counter itch relief treatment," said Sean Edwards, president and CEO, Cosmederm Bioscience. "They validate our claim that TriCalm is more effective at relieving itch than hydrocortisone 1%, providing fast-acting itch relief without the potential side effects of steroid-based creams."

 

TriCalm was tested against two objectives: first, to assess the anti-itch effect in reducing intensity and duration of itch, and second, to compare TriCalm's effectiveness against typical anti-itch products containing diphenhydramine 2% and hydrocortisone 1% active ingredients.

 

This double-blinded, vehicle-controlled, randomized, crossover study recorded itch intensity and duration in 48 healthy subjects before and after skin treatment with TriCalm hydrogel, diphenhydramine 2%, hydrocortisone 1% and hydrogel vehicle, used as a control.

 

TriCalm hydrogel produced the highest itch reduction in all three areas measured: itch intensity, itch duration and total itch perceived – a combined measure of both intensity and duration that represented the overall itch experienced by the subject. Conclusively, the study found that TriCalm hydrogel was six times more effective than diphenhydramine 2%, and eight times more effective than hydrocortisone 1% at reducing the sensation of itch on the subjects' skin.  

 

Itch is the most common complaint in dermatology clinics. The study was designed to demonstrate effective, steroid-free itch relief.