Vernalis launches 12-hour Tuzistra XR

BERWYN, Pa. — Vernalis Therapeutics announced Tuesday that its Tuzistra XR (codeine polistirex and chlorpheniramine polistirex) extended release syrup has been made available ahead of cold and flu season. The 12-hour dosage strength syrup is meant to treat coughs from the cold or upper respiratory allergies in adults 18 years of age and older.

“The launch of Tuzistra XR marks a significant milestone for Vernalis Therapeutics and demonstrates our capability to build a broad portfolio of unique, long-acting, liquid formulations of branded prescription cough cold products in the U.S. market,” Vernalis Therapeutics SVP commercial operations Tom Parker said. “We are pleased to offer physicians and patients a proprietary Schedule III, 12-hour, codeine and chlorpheniramine combination liquid product to help manage cough and cold symptoms in advance of this year's cough cold season.”

The 12-hour formula has its advantages for prescribers and patients, the company said.

“Until now, physicians looking to prescribe a codeine-containing antitussive have been limited to short-acting medications," Dr. Pascal Borderies, Vernalis Therapeutics SVP medical affairs said. “Tuzistra XR's extended-release liquid delivery system allows for less frequent dosing than traditional codeine cough syrups. This makes it a viable option for patients looking to extend the relief of cough and symptoms associated with upper respiratory allergies or the common cold with twice-daily dosing.”